Fremantle captain Nat Fyfe headlines a group of four players that will come in for Freo’s clash with St Kilda on Saturday at Metricon Stadium.
Fyfe is joined by defender Brennan Cox, forward Travis Colyer and midfielder Blake Acres, who will make his Freo debut against his former team.
Injured trio Griffin Logue (toe), Reece Conca (hamstring) and Jesse Hogan (calf) come out of the team alongside defender Taylin Duman (omitted).
Duman, Bailey Banfield, Mitch Crowden and Connor Blakely are Freo’s emergencies.
Fyfe’s return means he misses only one game after sustaining a minor hamstring injury against Gold Coast in round four.
Acres has been named on the bench and is set to slot in on the wing in his first game in purple.
His only previous hitout for Freo came in the Marsh Community Series against Carlton, where he had 31 disposals.
The 24-year-old sustained a hamstring injury at training in the week following the game and later picked up a cork to his calf at training prior to Freo’s arrival at the hub on the Gold Coast.
While Acres can also play as an inside mid, senior coach Justin Longmuir said he intends to play Acres on the wing.
“From day one we tried to settle him down on the wing and make him a one position player,” Longmuir said.
“That’s what he wanted and that’s what we wanted too…rather than throwing him around in different positions.”
Cox will play his first game since round three, when he had 15 disposals and five marks against Port Adelaide.
The 195cm defender may line up on the Saints’ Max King, who has kicked seven goals from five appearances this season.
Colyer returns to the Fremantle lineup after his late omission due to a migraine against Adelaide.
Bouncedown for the clash is at 10.35am (WST) on Saturday and the game will be broadcast live into Perth on Channel 7 and nationally on Foxtel.
The match will also be streamed live via Kayo and AFL Live Pass.
TEAM v SAINTS
Back: Stephen Hill, Brennan Cox, Ethan Hughes
Half Back: Nathan Wilson, Luke Ryan, Hayden Young
Centre: Darcy Tucker, Nat Fyfe, James Aish
Half Forward: Adam Cerra, Rory Lobb, Sam Sturt
Forward: Travis Colyer, Matt Taberner, Michael Walters
Ruck/followers: Sean Darcy, David Mundy, Andrew Brayshaw
Interchange: Brett Bewley, Caleb Serong, Lachie Schultz, Blake Acres
Emergencies: Bailey Banfield, Mitch Crowden, Connor Blakely, Taylin Duman