UPDATE: Fremantle have made a late change to their starting 22, with Alex Pearce withdrawn from the line-up with a calf injury
Pearce has been replaced by forward Bailey Banfield who will start the game on the field, with Liam Henry now the medical sub.
The game will be Banfield's 16th of the season and Henry's first of the season as a medi sub.
St Kilda have designated half back Ben Long as their medi sub.
The game will be Caleb Serong's 50th after the no.8 pick made his debut in round four of the 2020 season.
Bouncedown for the clash is at 7.25pm EST (5.25pm WST) and will be broadcast live into WA on 7mate, Fox Footy and can be streamed on Kayo.